Using Electrophoresis To Determine The Sickle Cell Disease I essays

Using Electrophoresis To Determine The Sickle Cell Disease I essays Title: Using Electrophoresis To Determine The Sickle Cell Disease In Hemoglobin Electrophoresis is the movement of charged molecules under the influence of an electric field. Because amino acids and proteins are charged molecules, they migrate in an electric field at appropriate pH values. Hemoglobin is the major protein inside red blood cells. Its primary function is to transport oxygen. When used in an electrophoresis experiment traits and diseases are easily determined because of where the proteins and amino acids migrate on the gel plate. When oxygen concentration in the blood decrease the defective molecule forms long crystals inside the red blood cells to elongate and assume a sickle shape. The crystallized hemoglobin also damages the cell membrane so that the cells become very fragile. Sickle cell disease is a genetic disorder that is caused by a single amino acid change in the hemoglobin. In this particular experiment, electrophoresis was used to distinguish whether or not each sample of blood was normal hemoglobin, blood with the sickle cell tra it, or blood with the sickle cell disease. The hypothesis concerning this experiment was that considering the hemoglobin of sickle cell disease has a different amino acid that normal hemoglobin or a carrier for the disease it will migrate to a different space on the gel plate than the normal hemoglobin or carrier. The hemoglobin that is a carrier for sickle cell disease has both amino acids, therefore, it will fill both the space designated for normal hemoglobin as well as the diseased hemoglobin. Predicted Resulted As seen in the charts supplied above the predicted outcome was achieved in the performed experiment. In column one the sample was read as normal hemoglobin, in column three it was sickle cell, and finally in column ...

How to Use the French Conditional (le Conditionnel)

How to Use the French Conditional (le Conditionnel) The French conditional (le conditionnel) mood is very similar to the English conditional mood. It describes events that are not guaranteed to occur, those that are often dependent on certain conditions. While the French conditional mood has a full set of conjugations, the English equivalent is simply the modal verb would plus the main verb. Le Conditionnel: If...then The French conditional is mainly used in  if...then  constructs. It  expresses the idea that  if  this were to happen,  then  that would be the result.   While French uses the word  si  in the if or condition clause, it does not use a term for then in the result clause.  The conditional verb itself is used in the result (then) clause, while only four other tenses are permitted in the  si  clause:  prà ©sent, passà ©Ã‚  composà ©, imparfait,  and  plus-que-parfait. Il mangerait sil avait faim:  He would eat if he were hungrySi nous à ©tudiions, nous serions plus intelligents:  If we studied, (then) we would be smarterIl mangerait avec nous si nous linvitions:  He would eat with us if we invited him Special Cases: Vouloir and Aimer The verb vouloir (to want)  is used in the conditional to express a polite request: Je voudrais une pomme:  I would like an appleJe voudrais y aller avec vous:  I would like to go with you However, you cant say si vous voudriez to mean if you would like, because the French conditional can never be used after si. The verb aimer (to like, love)  is used to express a polite desire, sometimes one that cannot be fulfilled: Jaimerais bien le voir:  I would really like to see itJaimerais y aller, mais je dois travailler:  I would like to go, but I have to work Conjugating le Conditionnel Conjugating the conditional  may be one of the simplest French conjugations youll encounter. There is only one set of endings for all verbs. Most of them - even many that are irregular in the present tense - use their infinitives as the root. There are only about two dozen  stem-changing  or  irregular verbs  that have irregular conditional stems but take the same endings. To show you how easy conditional conjugations are, lets take a look at how it applies to different types of verbs. Well use  jouer  (to play) as our regular  -er  example,  finir  (to finish) as our irregular  -ir  example, and  dire  (to say) as one exception to the rules. Subject Ending Jouer Finir Dire je -ais jouerais finirais dirais tu -ais jouerais finirais dirais il -ait jouerait finirait dirait nous -irons jouerions finirions dirions vous -iez joueriez finiriez diriez ils -aient joueraient finiraient diraient Notice how we had to drop the e in  dire  before adding the conditional endings. This is the sort of change you will find in that handful of verbs that do not follow the standard conditional conjugation pattern. Other than that, you can see how easy it is to form the conditional from almost any verb, even the irregular ones. The Verbs That Don't Follow the Rules So which verbs are you going to have to pay attention to when it comes to the conditional verb mood?  Dire  and other verbs that end in  -ire  are easy compared to some of the others, a few barely resemble the infinitive form while others take on more subtle changes.   The following verbs are irregular in the conditional mood. Notice how the stems change and that they do not use the infinitive form like the other verbs do. There are two rules here: The conditional stem always ends in r.  The exact same verbs are irregular in the  future tense  and use the same stems. When conjugating these into the conditional, simply attach the endings noted above according to the subject pronoun in your sentence. Infinitive Verb Conditional Stem Similar Verbs acheter achà ¨ter- achever, amener, emmener, lever, promener acquà ©rir acquerr- conquà ©rir, s'enquà ©rir appeler appeller- à ©peler, rappeler, renouveler aller ir- avoir aur- courir courr- concourir, discourir, parcourir devoir devr- envoyer enverr- essayer essaier- balayer, effrayer, payer essuyer essuier- appuyer, ennuyer à ªtre ser- faire fer- falloir faudr- jeter jetter- feuilleter, hoqueter, projeter, rejeter nettoyer nettoier employer, noyer, tutoyer,-ayer stem-changing verbs pleuvoir pleuvr- pouvoir pourr- savoir saur- tenir tiendr- maintenir, obtenir, soutenir valoir vaudr- venir viendr- devenir, parvenir, revenir voir verr- revoir vouloir voudr-

Guest lecturer reports Essay Example | Topics and Well Written Essays - 750 words - 1

Guest lecturer reports - Essay Example Thus engineers are part of the problem solving process and apply an analytical approach in providing solutions. The knowledge of social construction of technology aids in the comprehension of societal problems in relation to the existing economic needs of the people. Therefore engineers are able to device appropriate solutions technically to suit the changing economic trends. Engineers are social scientific practitioners who mainly link scientific discoveries and the commercial applications to meet the day today societal and consumer needs (Anastasia & Reshma, 2009). This is incredibly plausible through the ideas this clever bunch of professionals put forward to act as economic solutions to technical problems in relation to the application of scientific principles. Sociology of technology is a theory that argues on the basis of human action shaping technology. One of the distinctive characteristics of technology is that it’s socially shaped i.e. a new technology available at o ne time may be developed and implemented following consumer interests. Thus a working technology is rendered unsuccessful when it does not meet the prevailing standards of consumer interests (Bijker, Wiebe, Thomas, Hughes, Trevor, & Pinch, 1987). Engineering socio-technical system defines societal roles in determining what design should be used by engineers to construct a device that is generally accepted, at certain limits. It is this design that influences the implementation of a particular technology at a particular time. As a theory and a methodology, SCOT analyses the causes of success and failure to a particular technology through formalizing appropriate scientific procedures and principles. This argument is evident in the evolution of bicycle, innovating different designs. The first invention of the bicycle was the velocipede, which was difficult to mount, had a poor braking system and the front wheel tended to clean itself on the cyclist's trousers while negotiating bents. T his paved way for penny-farthing part of the developmental process to find an efficient form of personal transport. Similarly, it took a cyclist some practice to learn how to get into and off the high wheel. This, accompanied by risks of tumbling for longer distances when one lost control, called for a new invention. The bicyclette, also known as safety bicycle, is the first chain-drive with advantages over the other inventions. The bicycle invention may be summarized in an innovation model continuum, as shown below. The linear innovation model suggests that the technical change in bicycle occurs in a linear fashion as illustrated in the flow chart below. On the other hand, multi-directional model provides a wider view on the relationship of the subsequent designs (Sismondo, 1993). Illustration 1: Linear Model of Innovation Illustration 2: Multi-directional Model Social analytical approach spells out clearly the diverse problems that need corrections, thus, which are very fundamenta l for my understanding. The interpretive flexibility stage analyses the problems affecting the male, elderly and female cyclists. By this, understand the requirements of the elderly, male, and female cyclists. The ordinary bicycle contributed major to the development of bicycles albeit having limitations on the elderly cyclists and female cyclists. It was rendered for young and athletic men who were thought to withstand its tumbling menace when it suddenly hit a rough surface, and also the rider's position over the centre of the

Enhancing Literature for students of English as second Language Research Paper

Enhancing Literature for students of English as second Language - Research Paper Example Research shows that education is a long prescription and a short on description and this statement holds true for literacy instructions given for English language learners or students who use English as a second language (ESL). ESL students will represent a wide range of cultures and language skills and are the easiest to take note of in schools as they are enter into classrooms without knowing how to have a conversation with other students in English. These students will remain silent in class as they are trying to adjust in the new environment and culture and this silent period presents a time of great discomfort for the students as they feel as if they do not belong. Teachers working with these students will require theories and conceptual models and frameworks that are aimed at ensuring that the students easily adapt in the new environment and that their learning goes on smoothly without language barriers affecting their success in education (Jimenez and Gersten, 1994). Teachers will require to incorporate comprehensive input, cognitive academic language proficiency and the natural language approach in the effort of making ESL students learn without language barriers interfering with their success. Research reveals that there needs to be a considerable amount of guidance and innovative ideas that will enable ESL students to adapt in the new environment and learn English, and this will make the classroom conducive for learning. (Jimenez and Gersten, 1994). Teachers are required to enhance the approach they use to educate ESL students so as to make their classrooms conducive for the great numbers of ESL students. There is a general increase in the number of ESL students in the United States classrooms, and this means that there are cases when teachers without training on how to teach them attend to these students. Teachers can be asked to teach students of Non-English backgrounds , and this presents a milestone as the students may not be able to read and writ e well in their native language or in English hence the need for special attention and programs aimed at improving the literacy learning skills (Jimenez and Gersten, 1994). Thus, teachers are faced with the task of building literacy, develop writing expression ability and enhance the growth of the English language for the student at the same time. This is extremely challenging for teachers, and even the most experienced ones may have problems in simultaneously building these capabilities. Factors Affecting Second Language Acquisition There are various factors that will affect students’ ability to acquire a second language despite the fact that students will have varying patterns, speed and acquiring styles. Some students will easily take off and become quickly conversant without much effort and for others this will present a huge challenge. Some students will continue to struggle with learning English despite being engaged in constant and lengthy periods of being exposed to t he language being learnt (English). Learner characteristics or personal traits affect the ESL students in their effort to acquire literal efficiency. These are the characteristics that are specific to an individual and they will include attitude, motivation, personality, learning styles and attitudes. Research shows that self confident students and those that have sociable personalities will have the courage to attempt verbal communication with other students and these interactions will make them to adapt easily to the new environment (Reid, 2002). Learner characteristics will affect how the student responds to instructions, which will influence the student’s ability to learn. Situational or environmental factors are concerned with issues that are external to the

Copyright Law and Technological Advances Essay Example | Topics and Well Written Essays - 3500 words

Copyright Law and Technological Advances - Essay Example In the context of the Internet, copyright law operates in such a way that the interests of the genuine owner of creative works, and the rights to the public to access such works are balanced. Hence, protecting creativity in the context of the Internet implies the promoting of intellectual development. In the absence of such protection for intellectual creativity, public access to information would be restricted. Hence, copyright law has to provide sufficient protection to copyright owners and also restrict the infringements that take place on the internet. Damages for such infringements have to be compensated to the owner of copyrights. The infringements of copyrights are increasing in number, due to the rapid expansion of the Internet. The relevant legislation has not kept apace with this proliferation of the Internet. It remained static and was unable to cope with the new and innovative methods of infringing copyrights.

Corporate strategy assigment Essay Example | Topics and Well Written Essays - 1750 words

Corporate strategy assigment - Essay Example The company has employed more than ten thousand professionals in 27 countries globally. The company enjoys considered client base that include insurance companies, corporations, sovereign wealth funds, banks, pension companies and endowment foundations. The company offered integrated services to its clients including enterprise management, strategic advisory services and risk management services. The company has more than US $ 3.67 trillion in fixed income securities, real estates, equity funds and alternative investments (Grind 40). Business model development Black Rock Inc has implemented an excellent business model. The company recognizes the changing business environment requires innovative products. The company has a global scale approach to its operations and enables clients have a local reach to its services. The company is also client-focused since it provides integrated services to its client portfolio. The business model is aimed at facilitating efficiency, enhancing teamwo rk across the globe and offering tailor-made products that meet the client needs. Organisational culture One of the core assets of the organisation is an organisational culture that is aimed at meeting client needs. ... The company adds value to client solutions by the constant evolution of new product offerings. Through offshore funds, unit trusts and managed accounts, the company has been able to meet the unique needs of each client in the world. Human resources The company has invested in highly qualified risk management analysts and other key staff. For instance, the company has recently recruited experienced staff from some of the major competitors. The risk and quantitative analysis teams utilize a global and integrated approach in analysis of the market risks while also maintaining a regional orientation. The human resources are able to use the best practices in investments and risk management activities. Distribution and logistics The company has office locations in about 27 countries. The company has also enhanced the global reach through offering investment opportunities through the internet. The company has established partnerships with other financial intermediaries in order to increase the client base. Porter’s Five Forces Supplier power Maintaining of a good relationship with current clients is very important for Black Rock Inc. Current clients usually refer new clients due to their satisfaction with services that they receive from an organization. The company recognizes this and has invested on building long term relationships with their clients. One of the critical assets of the company is a good reputation that is maintained by the investor relations segment of the business (Schermerhorn 2010). Black rock Inc has been able to gain a high ranking among potential employees through its performance in the industry. Therefore, the company gets a highly qualified pool of applicants to choose from when hiring employees. The employees are

Career Path Planning Report Essay Example | Topics and Well Written Essays - 3000 words

Career Path Planning Report - Essay Example Designing and implementation of software refers to the task of software development. This has grown to cover web development aspects, interface design, issues concerning securities, mobile computing among others. Most graduates usually follow this career path. Despite having taken a degree being sufficient to venture into this career, some graduates decide to undertake a master’s degree (Lopatto, 2004). Career opportunities is provided in various settings such as software companies, computer services companies, industries, health sectors, banking among other sectors. Coming up with new ways of computer use requires one to come up with various innovations in computer technology applications. This pathway includes graduate work that is advanced, positioning one in an industrial research or research in a university. Coming up with effective ways in solving computing problems needs one to apply knowledge and theory in computer science to come up with solutions to computational problems. This needs graduate work to PhD level, later positioning in Research University or development laboratory or industrial research (Goode, 2008). On completion of my computer science course, two career jobs of my choice are web designer and software tester. Having gained all the skills and knowledge over the years of my degree course, it would be easier to handle the two careers in the real life situation. As a software tester, one is engaged in quality assurance level of development of software and deployment. The person is involved in conducting both automated and manual software tests to ensure their fitness for the purpose they are meant for. This career of software testing involves software and system analysis to eradicate risks and prevent other software issues. The software tester role is tied to development of software systems and other technical products such as electronic goods, vehicles, healthcare and defense.